Medical hair therapy, derma utoquai Zurich
Medical hair therapy · Zurich

Six active ingredients.
One plan.

Not every case of hair loss needs surgery straight away. For many people it starts with a drug, the right one, at the right dose, properly monitored. Dr Sussan Rosenthal puts every treatment plan together herself.

93 %Less visible loss / 5 yrs
3–6Months until assessment
0Surgical procedures
MaintenancePrimary treatment goal
PermanentWorks only while used
12 mthsUntil the full effect
Can be combinedWith PRP, mesotherapy, transplantation
Treatment overview

What drug therapy can do can achieve.

Medication halts the loss and thickens the hair you have. It does not create new follicles. That is why it always starts with a diagnosis, and an honest account of what is achievable.

Diagnosis first

Trichoscopy, medical history and, where needed, blood work. Only once the cause is clear do we discuss a drug, not the other way round.

Selection and dose

A regimen that fits your diagnosis, your routine and your plans. The one you can sustain beats the one that is strongest on paper.

Monitoring over time

Standardised progress photographs and follow-up appointments. At twelve months we assess honestly whether the treatment is doing what it should.

The drug selector

Six options. One click.

Select a drug, how it works, how it is used, the evidence and the safety profile appear immediately.

Minoxidil, topical

A potassium channel opener: it increases blood flow to the scalp and extends the hair's growth phase. The longest-documented drug for hereditary hair loss, and approved for both sexes.

ApplicationTopical, once or twice daily
Concentration2% or 5%
First resultsAfter 3–6 months
Typische ReaktionDryness, itching

Evidence

+45 %
More growth on 5% than on 2% at 48 weeks (n = 393). 5 %2 %Placebo Increase in non-vellus hairs at week 48.

Finasteride, oral

A type II 5-alpha-reductase inhibitor. It lowers DHT in the scalp and in serum, acting on the real cause: the hormonally driven shrinking of the follicle. Prescription only, and for men only.

Application1 mg orally, daily
Approved forMen
DHT reduction in the scalpAround 64%
AssessmentAfter 12 months

Evidence

93 %
Relative risk reduction for further visible loss over 5 years, 95% CI 89–97 (n = 1,553). 93% The side-effect profile is discussed before anything is prescribed.

Minoxidil, oral · LDOM

Low-dose oral minoxidil, under 5 mg a day, an option where the topical form is not tolerated or simply cannot be kept up. It acts systemically, so it requires cardiac assessment and ongoing monitoring.

Application0.25–5 mg daily
RequirementCardiac assessment
Most common reactionHypertrichosis, 24%
StatusOff-label

Evidence

+47,1
hairs/cm² expected increase in total density per +1 mg/day at 6 months (meta-regression). 0.5 mg5 mgDensity ↗ More effect, more side effects, the dose is found individually.

Fynzur® · topical finasteride

Finasteride 0.25% as a spray. A chitosan carrier deposits the drug around the hair bulb, where it inhibits 5-alpha-reductase, with a far lower systemic load than the tablet.

ApplicationOnce daily, 1–4 sprays
Active ingredientFinasteride 0.25%
Plasma levelOver 100× lower
AssessmentAfter 6 months

Evidence

20,2
Additional hairs in the target area at 24 weeks, oral 21.1, placebo 6.7 (phase III, 45 centres). OralTopicalPlacebo21,120,26,7 Comparable effect, lower systemic exposure.

Ketoconazolee 2%

Originally an antifungal, used in hair medicine for its anti-inflammatory effect on the scalp and a mild anti-androgenic action. Not a lead player, but a useful supporting one, particularly with a seborrhoeic scalp.

ApplicationShampoo, 2–4× weekly
RoleAdjuvant
Particularly forSeborrhoea, dandruff
TolerabilityVery good

Evidence

+7 %
Increase in hair shaft diameter at 6 months, comparable with minoxidil 2%. KetoconazoleeMinoxidil 2% A small cohort and open-label design, an adjunct, not a foundation therapy.

Alfatradiol

17-alpha-estradiol as a topical solution. It inhibits 5-alpha-reductase locally without meaningful systemic oestrogenic effect. In German-speaking countries it is used mainly in women when minoxidil is unsuitable or not tolerated.

ApplicationTopical, daily
FocusWomen
How it worksLocal 5-AR inhibition
Strength of evidenceModerate

Context

Stable
Alfatradiol mainly reduces the rate of shedding. It thickens less than minoxidil does. TherapyUntreated Schematic illustration of the treatment concept.
Why local beats systemic

The same effect.
Less body-wide exposure.

Dr Rosenthal looks first at locally acting options: PRP, SeffiHair®, polynucleotides or dutasteride mesotherapy. They work where the problem is, and avoid the systemic load oral drugs can bring. Only after that do we discuss tablets.

Serum DHT reduction at 24 weeks OralTopical 55,6%34,5% Piraccini et al., JEADV 2022
Who it suits

When medication makes sense – and when it cannot.

Useful for

  • Early to moderate findings – follicles that can still be reactivated
  • After the transplant – to protect the hair that has not been transplanted
  • When stabilising is the goal – preservation matters more than maximum density
  • Combination therapy – alongside PRP, mesotherapy or polynucleotides

Not suitable for

  • Vernarbende Alopezie – this needs a different assessment
  • Men planning to have children – 5-AR inhibitors are reviewed critically
  • Pregnancy and breastfeeding – most of these drugs are contraindicated
  • Unklare Ursache – diagnosis first, then treatment
Frequently asked questions

What patients ask first.

Generally yes. The effect lasts as long as the drug is used. Once you stop, over the following months things return to the course they would have taken untreated. Which is why a regimen you can actually keep up matters more than the theoretically strongest option.

Three to four months at the earliest, and reliably at twelve. Shedding can even increase in the first few weeks, as resting hairs move into the new growth phase together. This is well recognised and not a sign the treatment is failing.

Yes, and often that is exactly the sensible route. The mechanisms complement each other: drugs address the hormonal or vascular cause, regenerative treatments the environment around the follicle. We agree the right combination at the consultation.

No. Medication preserves and thickens existing hair; it does not create new follicles in bald areas. Equally, a transplant does not remove the need to protect your own hair with medication. In practice the two work together.

Consultation at Utoquai 39

A conversation. Not a sales pitch.

We look at your diagnosis and tell you honestly which drug suits you, and whether you need one at all.

Sources. Olsen EA et al., J Am Acad Dermatol 2002;47:377–85. · Lucky AW et al., J Am Acad Dermatol 2004;50:541–53. · Kaufman KD et al., J Am Acad Dermatol 1998;39:578–89. · Kaufman KD et al., Eur J Dermatol 2008;18:400–6. · Piraccini BM et al., J Eur Acad Dermatol Venereol 2022;36:286–94. · Randolph M, Tosti A, Skin Appendage Disord 2022;8:355–62. · Vañó-Galván S et al., Dermatol Ther 2020;33:e14106. · Piérard-Franchimont C et al., Dermatology 1998;196:474–7.

Please note. This page is for general information and does not replace medical advice. The drugs named are prescription-only or require a medical indication; some uses are off-label. Individual results vary.